Our guide to every Week 5 NFL game: Matchup previews, predictions, picks and nuggets

The Week 5 NFL schedule for the 2025 season brings immoderate breathtaking matchups.

Browns rookie QB Dillon Gabriel is making his NFL debut successful London against the Vikings. Old teammates successful Carolina, QBs Baker Mayfield and Sam Darnold, volition look disconnected again successful the Bucs-Seahawks matchup. And Commanders QB Jayden Daniels makes his instrumentality from injury against the Chargers.

We person you covered with everything you request to know. Our NFL Nation reporters instrumentality you wrong the locker country with the champion happening they heard this week, and ESPN Research provides a cardinal stat to cognize and a betting nugget for each contest. Plus, analytics writer Seth Walder makes a bold prediction for each matchup, and phantasy expert Eric Moody shares fantasy football intel. We besides person Football Power Index (FPI) matchup prime ratings (out of 100) and crippled projections, and 3 analysts -- Pamela Maldonado, Moody and Walder -- springiness america last people picks for each game.

Let's get into the afloat Week 5 slate, which culminates with a "Monday Night Football" matchup betwixt the Chiefs and Jaguars connected ESPN. (Game times are Sunday unless different noted.)

Jump to a matchup:
CLE-MIN | DEN-PHI | HOU-BAL
LV-IND | DAL-NYJ | MIA-CAR
NYG-NO | TB-SEA | TEN-ARI
WSH-LAC | DET-CIN | NE-BUF
KC-JAX

Thursday: SF 26, LAR 23 (OT)
Bye: ATL, CHI, GB, PIT

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