Sep 22, 2025, 12:58 PM ET
Week 4 gets underway with a matchup of NFC West rivals erstwhile the Arizona Cardinals big the Seattle Seahawks connected "Thursday Night Football."
Sunday nighttime features Micah Parsons and the Green Bay Packers hitting the roadworthy to instrumentality connected the Dallas Cowboys.
The week wraps up with a "Monday Night Football" doubleheader, arsenic the New York Jets sojourn the Miami Dolphins (7:15 p.m. ET connected ESPN) and the Denver Broncos big the Cincinnati Bengals (8:15 p.m. ET connected ABC).
Here's a look astatine the likelihood for each Week 4 game.
Odds arsenic of work time. For the astir existent odds, sojourn ESPN BET.
Jump to:
SEA-ARI | MIN-PIT | NO-BUF | LAC-NYG
WSH-ATL | PHI-TB | CLE-DET | CAR-NE
TEN-HOU | JAX-SF | IND-LAR | CHI-LV
BAL-KC | GB-DAL | NYJ-MIA | CIN-DEN


Seattle Seahawks vs. Arizona Cardinals -1.5
Thursday, 8:15 p.m., Prime Video
Money Line: Seahawks (-105); Cardinals (-115)
Total: 43.5; Opened: 44.5
FPI favorite: Cardinals by 0.8 with a 52.47% probability to triumph the crippled outright

Minnesota Vikings -2.5 vs. Pittsburgh Steelers
Sunday, 9:30 a.m., NFL Net, NFL+
Money Line: Vikings (-150); Steelers (+130)
Total: 40.5; Opened: 41.5
FPI favorite: Vikings by 3.1 with a 57.18% probability to triumph the crippled outright

New Orleans Saints vs. Buffalo Bills -15.5
Sunday, 1 p.m., CBS
Money Line: Saints (+900); Bills (-1800)
Total: 47.5; Opened: 48.5
FPI favorite: Bills by 13.3 with a 79.67% probability to triumph the crippled outright

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